Question: Why is atenolol contraindicated in pregnancy?

Atenolol can cause fetal harm when administered to a pregnant woman. Atenolol crosses the placental barrier and appears in cord blood. Atenolol use in pregnant women resulted in children born small in size with low sugar and slow heart rate.

Is it safe to take atenolol while pregnant?

The small number of available studies on beta-blockers used in pregnancy, in general, did not find a higher chance for birth defects. Can taking atenolol cause other pregnancy complications? Atenolol has been associated with reduced growth of the baby (smaller in size and/or low birth weight).

Why are beta blockers contraindicated in pregnancy?

(10-14) However, beta-blockers cross the placental barrier and are associated with several adverse effects, such as delayed intrauterine growth, respiratory depression, neonatal bradycardia and hypoglycemia, particularly when treatment is started early on in the pregnancy (i.e. at 12–24 weeks).

Does atenolol cause birth defects?

Are there any risks of taking atenolol during pregnancy? Atenolol belongs to a family of medicines called beta blockers. There are no concerns that beta blockers cause birth defects, stillbirth or preterm birth. Women taking beta blockers may be more likely to have a small baby.

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Which beta blocker is not safe in pregnancy?

Conclusions The authors found that exposure to β-blockers during pregnancy was associated with being born SGA, preterm birth and perinatal mortality. Our findings show that labetalol is not safer than other β-blockers during pregnancy.

What is the safest blood pressure medication during pregnancy?

Methyldopa has been used for decades to treat high blood pressure in pregnancy and it appears to be safe. Labetalol has been extensively studied and has become increasing prescribed in pregnancy. Labetalol is now commonly used as a first-line treatment choice. Nifedipine is also sometimes used in certain situations.

Can you breastfeed while taking atenolol?

WHO suggests to avoid if possible, especially if the infant is premature or less than 1 month old and monitoring the infant for adverse effects such as bradycardia, hypotension and cyanosis (3). The American Academy of Pediatrics recommends caution regarding the use of atenolol in nursing mothers (4).

Are beta blockers safe to take during pregnancy?

Beta-blocker exposure in pregnancy does not increase risk for fetal cardiac anomalies after adjusting for maternal comorbidities, according to a research letter published in JAMA Internal Medicine. “Beta-blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women.

Can beta blockers cause birth defects?

Beta-blockers used to treat hypertension during the first trimester of pregnancy don’t appear to increase the risk that babies will be born with birth defects or cardiac malformations, according to an analysis of observational data on more than 18,000 women across five Nordic countries and the United States.

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Can a pregnant woman take beta blockers?

Perspective: Beta-blockers are a first-line medication for hypertension during pregnancy and are also used during pregnancy for various other maternal cardiac conditions.

How do I stop taking atenolol?

Do not stop taking atenolol suddenly, especially if you have heart disease. This can make your condition worse. If you want to stop taking your medicine, speak to your doctor. They may recommended reducing your dose gradually over a few weeks.

What are the side effects of atenolol 25 mg?

Atenolol side effects

  • cold hands and feet.
  • constipation.
  • diarrhea.
  • dizziness.
  • headache.
  • reduced sex drive or impotence.
  • shortness of breath.
  • unexplained tiredness.

Why is losartan contraindicated in pregnancy?

Losartan should not be used during the second and third trimesters of pregnancy because it may be harmful to a developing baby. It’s not recommended in the first trimester unless considered essential by your doctor.

Do beta blockers cross placenta?

β-Blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women. Despite the common use of this class of medication, data that support its safety are limited. β-Blockers cross the placenta and potentially can cause physiological changes in the fetus.

What pregnancy category is atenolol?

Atenolol falls into category D. It has been shown that use of atenolol in pregnant women caused some babies to be born with problems. Atenolol can cause fetal harm when administered to a pregnant woman. Atenolol crosses the placental barrier and appears in cord blood.

Is metoprolol bad for pregnancy?

Metoprolol did not cause birth defects when given to animals early in pregnancy. A study of a large number of pregnancies found that beta-blockers did not cause heart defects in babies. Does taking metoprolol cause other pregnancy complications? Metoprolol has been associated with reduced growth of the baby.

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